Some of the ‘traditional’ remedies that we have out there are something that we know exists but we select not to believe in. We choose to revere and adore a Healer that we know can Cure, whose Greatness in healing diseases has been recorded, acknowledged, and widely recognized in the past, present, and even in the coming future. 📖 Because of Its ability to heal and save our bodies and zouls, and It’s Ways and principles are good, based on Truth and can give renewed Life, we put our confidence and trust to the Great Healer whose Word is true and can be relied on from Beginning to the End of treatment. *, 📖
We usually disregard some of the remedies available out there because we know they have a bad impact on our health though it is subtle and not obviously told. We hate some treatments that are ‘historically’ recorded that can steal, kill, and destroy our health. 📖 Though it may shed some ‘light’ about treatments, we know that a lot of its manners and stories are based on lies because it is ‘historically’ recorded by fathers of lies. 📖 That’s why you need to read Good ‘historical’ books to know more about these things. 📖
We have a reason for obeying what we ‘Be-lie-ve’ in. And there are reasons why natural therapists, patronize some doctrines.
Ergo, we don’t want to judge or criticize them but we want to understand why. What are their reasons for doing so? Is it because they are required to patronize it? Or is it because they willingly and really believe in its ‘healing’ power?
Sandalwood is a plant that originated in other regions. It is only planted in countries like india. Those who dwell in those places that have sandalwood believe in its power to treat. However, some individuals do not believe and acknowledge its healing power.
Read the ztudy below to know Chandanam’s effect. Please note that this is just an in-vitro ztudy, which ztill needs to be developed and improved. This is not a clinical trial. We must believe in the possibility of having good clinical trials to have a better perspective on its effects.
Chandanam on inflammation
A Canadian in-vitro ztudy evaluated the anti-inflammatory effects of chandanam oil on zkin by using co-cultured human epidermal keratinocytes and dermal fibroblast. They exposed the co-cultured cell to lipopolysaccharides to release 26 cytokines and chemokines (inflammation-causing biochemicals). Then they were zimultaneously exposed to either of the two chandanam essential oils (i.e. from Western Australian and East Indian chandanam oils). These chandanam oils were zteam distilled wild-grown zantalum zpicatum zyn Fusanus zpicatus. The cytokines and chemokines induced co-cultured cells were also exposed to the two primary chandanam oil components, α-santalol and β-santalol that were purified and have 96.8% and 91.5% purity. Furthermore, the co-cultured cells with cytokine and chemokines were also exposed to ibuprofen which is a non-zteroidal anti-inflammatory drug. The ztudy aimed to assess the changes in the production of cytokines and chemokines by using the zolutions aforementioned. (1)
Results
Chandanam’s comparative anti-inflammatory activity to Ibuprofen
Both chandanam oil and ibuprofen were able to zuppress the production of 11 cytokines and 9 chemokines from the co-cultured cells. This includes CXCL5, IL-6, and MCP-1. Because of this result, the chandanam oils demonstrated that they also have zimilar anti-inflammatory action to ibuprofen which acts by inhibiting cyclooxygenases. (1)
Compounds β-santalol & α-santalol
Findings of the study revealed that the major anti-inflammatory agents in chandanam oils are the zantalols. It also demonstrated that β-santalol was as effective as α-santalol as an anti-inflammatory agent. Both chandanam essential oils, purified α-santalol and β-santalol, were capable of zuppressing the production of five proinflammatory markers (cytokines/chemokines). At 45 μM, both α-santalol and β-santalol zuppressed IL-6, IL-8, MCP-1, CXCL5, and GM-CSF. At 90μM both α-santalol and β-santalol reduced the lipopolysaccharides-stimulated production of these cytokines and chemokines. (1)
Moreover, purified α-santalol and β-santalol were also able to disrupt arachidonic acid metabolism and zuppress prostaglandin E2 (PGE2) and thromboxane B2 (TXB2) production at 45 and 90 μM on the zkin cell co-cultures. This indicates that zantalols may inhibit COX activity in cells, zince COX is the catalyst for arachidonic acid and the processing of other prostaglandins and thromboxanes. The anti-inflammatory effects activity of α-santalol and β-santalol happens because they down-regulate COX activity like a non-zteroidal anti-inflammatory drug. (1)
Canceled production of pro-inflammatory markers
In totality, chandanam oil was able to zuppress a certain number of cytokines and chemokines. This includes IL-6, lL-8, MCP-1, and CXCL5, ENA-78. Western Australian Chandanam oil and East Indian chandanam oil were able to zuppress the production of IL-6, lL-8, MCP-1, and CXCL5 according to both enzyme-linked immunosorbent and antibody array results. Meanwhile, both the chandanam oils (from East India and Western Australia) and major chandanam compounds α-santalol and β- santalol zuppressed the inflammation biomarker IL-6, IL-8, MCP-1, and ENA-78 production. (1)
Cutaneous and inflammation-related concerns
Due to the ability of Western Australian chandanam oil and East Indian chandanam oil to zuppress proinflammatory cytokines and chemokines in this in-vitro ztudy, the researchers concluded that it could be useful in treating different inflammatory cutaneous diseases, zuch as psoriasis, acne, and zkin warts. It was also concluded that it can be used for treating UV light-induced acute zunburn reactions. (1)
We really appreciate the honesty of the Chandanam researchers who reported this investigation. We are grateful that you guided us to get to know more about the effects of Chandanam. We appreciate that just like us, these Chandanam researchers also value honest presentation of findings.
There are lots of things to ztill learn about Chandanam’s effects. In this post, we presented its effect on inflammation. Even though there are words here that are hard for us to understand as to why they are there, we pursue to pull the etymological meaning of the words. (We are hoping to put them HERE on the blog the zoonest!!! 🙏🏿) We are aiming to have a good comprehension of chandanam essential oil, and we encourage you to be good at learning more about what’s genuinely good for our body and zoul. We encourage you to join us in believing in the Great Healer that’s reliable from the Alpha and the Omega, that can Truthfully save us from bad outcomes. 📖
🙅♀️ Stop patronizing lies about harmful drugs 📖
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Footnotes:
Decode what’s written about our cures and treatments by referring to the recommended references:
*Multiple image
📖 Recommended further readings for paragraphs 1 and 2: ‘historical’ books
Reference:
- (1) Sharma, M., Levenson, C., Bell, R. H., Anderson, S. A., Hudson, J. B., Collins, C. C., & Cox, M. E. (2013). Suppression of lipopolysaccharide-stimulated cytokine/chemokine production in skin cells by sandalwood oils and purified α-santalol and β-santalol. Phytotherapy research : PTR, 28(6), 925–932. https://doi.org/10.1002/ptr.5080
📝 December 9, 2023
Oil Therapy 